Ecological Formulas - Allithiamine 50 mg 60 caps

Product Information

http://www.casereports.in/articles/6/3/Thiamine-Therapy-and-Refeeding-Syndrome-in-Extremely-Low-Birth-Weight-Infants.html

Personally, I am taking 50 mg of TTFD and 100 mg of sulbutiamine daily (as well as 150 mg of benfotiamine and 500 mg of thiamine hydrochloride). However, that doesn’t mean that would be right for you. If you are interested, here is a link to Isabella Wendtz’s blog where she talks about Thiamine and thyroid fatigue, and how she supplemented to help herself with it. https://thyroidpharmacist.com/articles/thiamine-and-thyroid-fatigue/I have Hashimoto’s and have not felt well under all the different meds I’ve tried over the past 5 years. I believe my condition is due to B1 deficiency, and the symptoms are getting more severe now that I’m 52. You previously advised to raise the dose “gradually” until symptoms yield. Do you ahve a general schedule to increase? For example, I waited at 150mg for a week, then I raised to 200mg. Once I realised what was going on I cut the sugar down to 10 – 20g per day. I haven’t cut it out completely at the moment since I struggle to eat enough on a pretty limited diet. I would like to try IV injections until my breathing problem is cured. There isn’t a lot of information on B1 IVs. Is there a therapeutic dose or IV drip to start with muscle shots as maintenance to continue? Or would you just recommend I use oral B1? I eventually develop tolerance to oral supplements and they stop working all together. Would upping the dose orally on Allthiamine theoretically compensate for any alcohol induced issues?

Why might I keep experiencing these “crashes” after exertion if my body is supplied with enough thaimine? Maybe my past chronic alcohol use, my IBS has a role in it, I have my ups and downs, but I just can’t handle the stress of my memory anymore, and I am only 33. I really do thank you both for the sterling work that you and Dr Lonsdale are doing- you are marvellous! I am experiencing an electrolyte imbalance (low phosphorus and potassium) after a period of fasting during Lent. I began eating normally again and experienced what I originally thought was Refeeding Syndrome. I had been diagnosed with this in the past and like this time, despite treatment and supplementing with up to 3,000 mg of Phosphorus and 160 mEq of Potassium, my blood levels are still low. We are trying to fix these deficiencies, but we are struggling. I started Lipothiamine 2 weeks ago, because Thiamine HCl and sublingual cocarboxylase didn’t help my B1 deficiency. It’s been a difficult start. Increased energy, slight POTS and IBS reduction; however, restlessness and anxiety has increased significantly. Also, increased pins and needles, and poor sleep. Maybe this is the paradox that is mentioned in several articles. This paradox is incredibly unpleasant and I understand why people stop treatment.

Other Derivatives

Diabetes mellitus-related morbidity and mortality is a rapidly growing healthcare problem, globally. Several nutraceuticals exhibit potency to target the pathogenesis of diabetes mellitus. The antidiabetic effects of compounds of garlic have been extensively studied, however, limited data are available on the biological effects of a certain garlic component, allithiamine. In this study, allithiamine was tested using human umbilical cord vein endothelial cells (HUVECs) as a hyperglycaemic model. HUVECs were isolated by enzymatic digestion and characterized by flow cytometric analysis using antibodies against specific marker proteins including CD31, CD45, CD54, and CD106. The non-cytotoxic concentration of allithiamine was determined based on MTT, apoptosis, and necrosis assays. Subsequently, cells were divided into three groups: incubating with M199 medium as the control; or with 30 mMol/L glucose; or with 30 mMol/L glucose plus allithiamine. The effect of allithiamine on the levels of advanced glycation end-products (AGEs), activation of NF-κB, release of pro-inflammatory cytokines including IL-6, IL-8, and TNF-α, and H 2O 2-induced oxidative stress was investigated. We found that in the hyperglycaemia-induced increase in the level of AGEs, pro-inflammatory changes were significantly suppressed by allithiamine. However, allithiamine could not enhance the activity of transketolase, but it exerts a potent antioxidant effect. Collectively, our data suggest that allithiamine could alleviate the hyperglycaemia-induced endothelial dysfunction due to its potent antioxidant and anti-inflammatory effect by a mechanism unrelated to the transketolase activity. It was later on when I was reading, really by accident, an article about Benfotiamine and the topic of B1 and the dry form of Beri Beri that the light went on for me. I had had leg weakness, the beginning of brain fog, neuropathy, and my bowel had basically stopped for a period of time.

I realize that I posted almost the same question twice.( I hadnt seen my post appear so thought it got lost somehow, now I see them both-) My apologies. This advice about thiamine supplementation has given me hope that perhaps I may find some level of improvement to my failing health. I was always a fit, slim and healthy person before Lupron and its effects have been utterly devastating, mentally and physically. I literally feel that nobody, even my family and friends believe what I have gone through. It has been a very lonely experience. A few of us were familiar with your work from perhaps 10 years ago, and several experimented with Benfotiamine at that time. While some saw some good gains from that, I feel that my son (now in his 20s) is seeing spectacular gains from the allithiamine after only a week or two–a much more obvious response than we saw with regular B vitamins or the Benfotiamine. I was able to wipe out Candida Krusei but I do still have yeast overgrowth (white toungue) due to IBS-C. I had elevated oxalates but not sure if I still have it. Would taking calcium citrate help breakdown oxalate foods? It’s been extremely difficult eradicating my yeast infections.POTS (not typical POTS, don’t get dizzy, just get uncomfortable and very high heart rate when standing or moving positions) I performed animal and clinical studies with thiamine tetrahydrofurfuryl (TTFD) for many years and found it to be an extremely valuable therapeutic nutrient. Any disease where energy deficiency is the underlying cause may respond to TTFD, unless permanent damage has accrued. Dr. Marrs and I believe that energy deficiency applies to any naturally occurring disease, even when a gene is at fault. For example, Japanese investigators found that TTFD protected mice from cyanide and carbon tetrachloride poisoning, an effect that was not shown by ordinary thiamine (Fujiwara, M. Absorption, excretion and fatal thiamine and its derivatives in the human body. In Shimazono, N, Katsura, E, eds. Beriberi and Thiamine. (pp 120-121) Tokyo, Igaku Shoin Ltd. 1965). They exposed a segment of dog’s intestine, disconnected it from its nerve supply and found that one of the disulfide derivatives stimulated peristalsis (the wavelike movement of the intestine). It is more than likely that TTFD could be used safely in patients with post operative paralysis of the intestine (paralytic ileus). Other Derivatives Currently consuming 100mg Lipothiamine. I do not yet see improvement with neuropathy, musculoskeletal pain, insomnia or anxiety with this, but I only added the Thiamine on June 18.